Cthrc1 cancer
WebMar 1, 2024 · Collagen triple helix repeat containing 1 (CTHRC1) is a glycosylated protein secreted during tissue repair, which reduces collagen matrix deposition and promotes cell migration. ... Studies have shown that CTHRC1 promotes colorectal cancer metastasis by inducing the Wnt/PCP signal transduction (Yang et al., 2015). In … WebJun 20, 2024 · This study aimed to investigate the prognostic value of CTHRC1, and further explore its association with immune infiltration in breast cancer. Methods: CTHRC1 …
Cthrc1 cancer
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WebOct 6, 2024 · Ke, Z. et al. Overexpression of collagen triple helix repeat containing 1 (CTHRC1) is associated with tumour aggressiveness and poor prognosis in human non … WebFeb 22, 2007 · We originally identified collagen triple helix repeat containing-1 (Cthrc1) in a screen for differentially expressed genes in normal versus balloon-injured arteries. 1 In …
WebCollagen triple helix repeat containing 1 is a protein that in humans is encoded by the CTHRC1 gene. Function. This locus encodes a protein that may play a role in the cellular response to arterial injury through involvement in vascular remodeling. Mutations at this locus have been associated with Barrett's esophagus and esophageal adenocarcinoma. WebFeb 15, 2024 · In CRC, the deletion of SMAD4 in cancer cells resulted in a decrease in S100A8+ monocytes in the tumor microenvironment . Furthermore, the release of Collagen Triple Helix Repeat Containing 1 (CTHRC1) by CRC cells induced M2 polarization of TAMs through TGFβ signaling and further promoted hepatic metastasis in mouse models …
WebMar 20, 2024 · CTHRC1 is widely upregulated in several solid tumors, including melanoma, gastrointestinal cancer, breast cancer, thyroid cancer, liver cancer, and pancreatic … WebMar 1, 2024 · Metastasis is the main cause of gastric cancer (GC) related death and the underlying mechanisms still remain unclear. Collagen triple helix repeat containing 1 (CTHRC1) protein is known to be involved in tissue remodeling processes and closely associated with carcinogenesis and metastasis in solid tumors, but the functional role of …
WebNov 14, 2024 · Although recent researches have reported that CTHRC1 upregulation in breast cancer promoting cell proliferation, invasion and migration could be through activating GSK-3β/β-catenin signaling, Citation 41 the exact mechanisms of CTHRC1 involvement in breast cancer remains unclear. Therefore, high expression of CTHRC1 …
WebMar 30, 2012 · The gene, collagen triple helix repeat containing 1 (CTHRC1), has been reported to increase in several kinds of human solid cancers and is associated with tumor invasion and metastasis.To date, the expression and function of CTHRC1 in gastric cancer (GC) have not been reported. chrome password インポートWebMar 21, 2024 · CTHRC1 (Collagen Triple Helix Repeat Containing 1) is a Protein Coding gene. Diseases associated with CTHRC1 include Barrett Esophagus and Adenocarcinoma . Among its related pathways are Wnt … chrome para windows 8.1 64 bitsWebMar 21, 2024 · Bioinformatics method. LUAD related data sets were acquired from Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA), as shown in Table 1.Expression differences of CTHRC1 between normal tissue and LUAD tissue were tested by t-test, and the effect of CTHRC1 expression on patient’s prognosis was detected with … chrome password vulnerabilityWebMar 1, 2024 · Collagen triple helix repeat containing 1 (CTHRC1) is a glycosylated protein secreted during tissue repair, which reduces collagen matrix deposition and … chrome pdf reader downloadWebThis study aimed to investigate the prognostic value of CTHRC1, and further explore its association with immune infiltration in breast cancer. Javascript is currently disabled in … chrome pdf dark modeWebApr 28, 2024 · CTHRC1 and LOXL2 are prominently upregulated pan-cancer matrisome genes. High CTHRC1 and LOXL2 expression is associated with disease progression and … chrome park apartmentsWebMay 13, 2024 · Here, by comparing the gene expression patterns in primary colorectal cancer (CRC) patients with or without metastasis, we found … chrome payment settings