Ribosomal protein phosphorylation
Webb22 mars 2024 · Early studies by Meijer’s group showed that rapamycin, an inhibitor of mTOR, induced autophagy and inhibited the phosphorylation of ribosomal protein S6 in … Webb1 jan. 2015 · The phosphorylation of ribosomal protein S6 (rpS6) has been described for the first time about four decades ago. Since then, numerous studies have shown that …
Ribosomal protein phosphorylation
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Webb11 apr. 2024 · Specifically, a network of conventional RBPs that includes the nucleolar protein nucleolin (Ncl) exhibits a significant enhancement in their RNA-binding activity upon oncogenic Kras induction. Using quantitative phospho-proteomics, we reveal that several of these RBPs, including Ncl, are phosphorylated downstream of Erk1/2. Webb22 mars 2024 · Early studies by Meijer’s group showed that rapamycin, an inhibitor of mTOR, induced autophagy and inhibited the phosphorylation of ribosomal protein S6 in rat hepatocytes [12], which provides the first evidence that inhibition of autophagy and phosphorylation of rpS6 are under control of the same signalling pathway [12].
WebbPhosphorylation of the N-terminal domain of ribosomal P-stalk protein uL10 governs its association with the ribosome. The presence of uL10 on the ribosomes is affected in … Webb1 juni 2024 · p70 S6 kinase (p70 S6K) is best known for its regulatory roles in protein synthesis and cell growth by phosphorylating its primary substrate, ribosomal protein …
WebbIn BHK cells infected with pseudorabies virus, there was a substantial increase in the phosphorylation of ribosomal protein S6. This increase occurred between 2 and 4 h … Webb28 nov. 2015 · The phosphorylation of ribosomal protein S6 (rpS6) has been described for the first time about four decades ago. Since then, numerous studies have shown that this modification occurs in...
WebbPhosphorylation of RPL12/uL11 regulates translation during mitosis Summary Emerging evidence indicates that heterogeneity in ribosome composition can give rise to …
Webb29 jan. 2015 · Ribosomal proteins, as primary components of ribosomes, are mainly responsible for protein synthesis in cells. In recent years, extra-ribosomal functions of these proteins have gained much attention, leading to increased interest in studying the genes encoding ribosomal proteins [ 9, 10 ]. the voice agriculteurWebb15 sep. 2005 · The regulated phosphorylation of ribosomal protein (rp) S6 has attracted much attention since its discovery in 1974, yet its physiological role has remained … the voice agathaWebbRibosomal proteins are fundamental building blocks for ribosome that is made through ribosomal biogenesis, a finely coordinated multi-step process engaging hundreds of … the voice agencyWebb29 dec. 2024 · The key markers of ribosome biogenesis were assessed via agarose gel-electrophoresis and RT-PCR. The rate of muscle PS was assessed by puromycin-based SUnSET method. As expected, 7-day HS resulted in a significant decrease in the inhibitory Ser9 GSK-3beta phosphorylation and an increase in GS-1 (Ser641) phosphorylation … the voice agatha christie versaillesWebbHydrophobic motif phosphorylation is not required for activation loop phosphorylation of p70 ribosomal protein S6 kinase 1 (S6K1) J Biol Chem. 2011; 286:23552–23558. [PMC … the voice agatha christie wirelessWebbThe ribosomal protein S6 (RPS6) is one of the well known downstream components of the TOR pathway. Ribosomal proteins have been known to have diverse functions in regulating cellular metabolism as well as protein synthesis. the voice ain\\u0027t no wayWebb17 sep. 2024 · Roux PP, Shahbazian D, Vu H, Holz MK, Cohen MS, Taunton J, et al. RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and … the voice agt